Johnny Depp is looking to go “mad” again.

According to Deadline, the “Pirates of the Caribbean” star is in final negotiations to reprise his role of the Mad Hatter in the sequel to Disney’s “Alice in Wonderland.

Not much has been revealed about the film’s plot, though “The Muppets” director James Bobin is set to helm the sequel, replacing Tim Burton.

The Burton-directed 2010 film starred Mia Wasikowska in the title role, with Helena Bonham Carter, Anne Hathaway and Alan Rickman (the “Harry Potter” franchise) in supporting roles.

The film grossed more than $1 billion worldwide, in part due to 3D sales, and though nothing has been confirmed, it’s likely that the sequel will be released in 3D as well.

The news comes after Depp’s “Lone Ranger” underperformed at the box office, recouping little more than half of the film’s budget since its release, according to Box Office Mojo.

The in-demand actor is also set to take on the role of Jack Sparrow in another “Pirates” sequel set to hit theaters in 2015.

What did you think of the first “Alice in Wonderland”? Do you plan to see the sequel?

Comment on this